Continuous acyin condensation method
The invention provides a continuous acyin condensation method. The method comprises the following steps: continuously dispersing metal sodium to obtain a sodium dispersion solution; mixing the sodium dispersion solution with a substrate, and carrying out continuous acyloin condensation reaction to o...
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| creator | HONG LIANG WANG YI LIU YANG CHEN XINGYU DING TIANDI LI ZHAOLUN TAO JIAN DAI RUIZHI |
| description | The invention provides a continuous acyin condensation method. The method comprises the following steps: continuously dispersing metal sodium to obtain a sodium dispersion solution; mixing the sodium dispersion solution with a substrate, and carrying out continuous acyloin condensation reaction to obtain a reacted solution; continuously quenching the reacted solution to obtain a quenched solution; carrying out continuous hydrolysis on the quenching solution to obtain a hydrolysis solution; carrying out continuous post-treatment on the hydrolysis solution to obtain a crude product solution; and continuously concentrating the crude product solution to obtain the alpha-hydroxy ketone compound, the structure of the substrate contains ester groups. The method can solve the problem of low purity of alpha-hydroxy ketone compound products prepared by batch reactions in the prior art, and is suitable for the field of synthesis of alpha-hydroxy ketone compounds.
本发明提供了一种连续化偶姻缩合的方法。该方法包括：将金属钠进行连续化分散，获得钠分散体溶液；将钠分散体溶液与底物混 |
| format | Patent |
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本发明提供了一种连续化偶姻缩合的方法。该方法包括：将金属钠进行连续化分散，获得钠分散体溶液；将钠分散体溶液与底物混</description><language>chi ; eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240621&DB=EPODOC&CC=CN&NR=118221506A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240621&DB=EPODOC&CC=CN&NR=118221506A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HONG LIANG</creatorcontrib><creatorcontrib>WANG YI</creatorcontrib><creatorcontrib>LIU YANG</creatorcontrib><creatorcontrib>CHEN XINGYU</creatorcontrib><creatorcontrib>DING TIANDI</creatorcontrib><creatorcontrib>LI ZHAOLUN</creatorcontrib><creatorcontrib>TAO JIAN</creatorcontrib><creatorcontrib>DAI RUIZHI</creatorcontrib><title>Continuous acyin condensation method</title><description>The invention provides a continuous acyin condensation method. The method comprises the following steps: continuously dispersing metal sodium to obtain a sodium dispersion solution; mixing the sodium dispersion solution with a substrate, and carrying out continuous acyloin condensation reaction to obtain a reacted solution; continuously quenching the reacted solution to obtain a quenched solution; carrying out continuous hydrolysis on the quenching solution to obtain a hydrolysis solution; carrying out continuous post-treatment on the hydrolysis solution to obtain a crude product solution; and continuously concentrating the crude product solution to obtain the alpha-hydroxy ketone compound, the structure of the substrate contains ester groups. The method can solve the problem of low purity of alpha-hydroxy ketone compound products prepared by batch reactions in the prior art, and is suitable for the field of synthesis of alpha-hydroxy ketone compounds.
本发明提供了一种连续化偶姻缩合的方法。该方法包括：将金属钠进行连续化分散，获得钠分散体溶液；将钠分散体溶液与底物混</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBxzs8rycwrzS8tVkhMrszMU0jOz0tJzStOLMnMz1PITS3JyE_hYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxzn6GhhZGRoamBmaOxsSoAQBAECcw</recordid><startdate>20240621</startdate><enddate>20240621</enddate><creator>HONG LIANG</creator><creator>WANG YI</creator><creator>LIU YANG</creator><creator>CHEN XINGYU</creator><creator>DING TIANDI</creator><creator>LI ZHAOLUN</creator><creator>TAO JIAN</creator><creator>DAI RUIZHI</creator><scope>EVB</scope></search><sort><creationdate>20240621</creationdate><title>Continuous acyin condensation method</title><author>HONG LIANG ; WANG YI ; LIU YANG ; CHEN XINGYU ; DING TIANDI ; LI ZHAOLUN ; TAO JIAN ; DAI RUIZHI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN118221506A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>HONG LIANG</creatorcontrib><creatorcontrib>WANG YI</creatorcontrib><creatorcontrib>LIU YANG</creatorcontrib><creatorcontrib>CHEN XINGYU</creatorcontrib><creatorcontrib>DING TIANDI</creatorcontrib><creatorcontrib>LI ZHAOLUN</creatorcontrib><creatorcontrib>TAO JIAN</creatorcontrib><creatorcontrib>DAI RUIZHI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HONG LIANG</au><au>WANG YI</au><au>LIU YANG</au><au>CHEN XINGYU</au><au>DING TIANDI</au><au>LI ZHAOLUN</au><au>TAO JIAN</au><au>DAI RUIZHI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Continuous acyin condensation method</title><date>2024-06-21</date><risdate>2024</risdate><abstract>The invention provides a continuous acyin condensation method. The method comprises the following steps: continuously dispersing metal sodium to obtain a sodium dispersion solution; mixing the sodium dispersion solution with a substrate, and carrying out continuous acyloin condensation reaction to obtain a reacted solution; continuously quenching the reacted solution to obtain a quenched solution; carrying out continuous hydrolysis on the quenching solution to obtain a hydrolysis solution; carrying out continuous post-treatment on the hydrolysis solution to obtain a crude product solution; and continuously concentrating the crude product solution to obtain the alpha-hydroxy ketone compound, the structure of the substrate contains ester groups. The method can solve the problem of low purity of alpha-hydroxy ketone compound products prepared by batch reactions in the prior art, and is suitable for the field of synthesis of alpha-hydroxy ketone compounds.
本发明提供了一种连续化偶姻缩合的方法。该方法包括：将金属钠进行连续化分散，获得钠分散体溶液；将钠分散体溶液与底物混</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY METALLURGY ORGANIC CHEMISTRY |
| title | Continuous acyin condensation method |
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