Continuous acyin condensation method

The invention provides a continuous acyin condensation method. The method comprises the following steps: continuously dispersing metal sodium to obtain a sodium dispersion solution; mixing the sodium dispersion solution with a substrate, and carrying out continuous acyloin condensation reaction to obtain a reacted solution; continuously quenching the reacted solution to obtain a quenched solution; carrying out continuous hydrolysis on the quenching solution to obtain a hydrolysis solution; carrying out continuous post-treatment on the hydrolysis solution to obtain a crude product solution; and continuously concentrating the crude product solution to obtain the alpha-hydroxy ketone compound, the structure of the substrate contains ester groups. The method can solve the problem of low purity of alpha-hydroxy ketone compound products prepared by batch reactions in the prior art, and is suitable for the field of synthesis of alpha-hydroxy ketone compounds. 本发明提供了一种连续化偶姻缩合的方法。该方法包括：将金属钠进行连续化分散，获得钠分散体溶液；将钠分散体溶液与底物混