Escherichia coli phage embedding method and application thereof

The invention belongs to the technical field of microorganisms, and discloses an Escherichia coli bacteriophage embedding method and application thereof, Escherichia coli bacteriophage liposome coating liquid is used for preparing a medicine for preventing and/or treating chicken air sacculitis, and the dosage of the Escherichia coli bacteriophage liposome coating liquid is 107-109 PFU/mL. The escherichia coli bacteriophage is RDP-EC-22027, and is preserved in the China General Microbiological Culture Collection Center on October 31, 2022, the preservation number is CGMCC No.45356, and the host bacterium is EC-22027. The escherichia coli bacteriophage has the advantages that the escherichia coli bacteriophage can be used for preparing the escherichia coli bacteriophage; the bacteriophage RDP-EC-22027 is prepared into lipidosome, so that the lipidosome can reach a focus more quickly and stay in a body for a longer time, has good controlled release property, and can improve the protection rate and reduce the de