Relecotinib phosphate tablet and preparation method thereof
The invention relates to the technical field of medicine preparation, in particular to a rucotinib phosphate tablet and a preparation method thereof. The rucotinib phosphate tablet is prepared from the following raw materials in parts by mass: 3 to 8 parts of rucotinib phosphate, 70 to 80 parts of f...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to the technical field of medicine preparation, in particular to a rucotinib phosphate tablet and a preparation method thereof. The rucotinib phosphate tablet is prepared from the following raw materials in parts by mass: 3 to 8 parts of rucotinib phosphate, 70 to 80 parts of filler, 1 to 5 parts of adhesive, 1 to 4 parts of disintegrating agent, 1 to 4 parts of flow aid, 1 to 10 parts of hydroxypropyl methyl cellulose, 2 to 6 parts of sodium alginate and 1 to 3 parts of carrageenan, according to the present invention, the prepared rucotinib phosphate tablet meets the quality standard, and the prepared rucotinib phosphate tablet has characteristics of good dissolution rate and high drug loading capacity.
本发明涉及药物制备技术领域,尤其是涉及一种磷酸芦可替尼片及其制备方法;一种磷酸芦可替尼片,包括以下质量份数的原料:磷酸芦可替尼3-8份、填充剂70-80份、粘合剂1-5份、崩解剂1-4份、助流剂1-4份、羟丙基甲基纤维素1-10份、海藻酸钠2-6份以及卡拉胶1-3份;本发明制备得到的磷酸芦可替尼片符合质量标准,且制备得到的磷酸芦可替尼片溶出度好、载药量高。 |
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