Pharmaceutical composition containing meloxicam as well as preparation method and application of pharmaceutical composition

The invention provides a pharmaceutical composition containing meloxicam and a preparation method and application thereof.The pharmaceutical composition comprises meloxicam, a composite solvent and an acidic pH regulator, the composite solvent is composed of a high-molecular compound, an alkaline compound and an aqueous solution, the high-molecular compound is selected from cyclodextrin or synthetic cyclodextrin and derivatives thereof. The meloxicam composition provided by the invention does not contain any organic solvent, can effectively avoid the generation of untoward effects of a medicinal preparation, ensures that the medicine is safer to use, and also reduces the pollution of the medicine to the environment in the preparation process. 本发明提供了一种含有美洛昔康的药物组合物及其制备方法和应用，所述药物组合物包括美洛昔康、复合溶剂和酸性pH调节剂，所述复合溶剂由高分子化合物、碱性化合物和水溶液组成，所述高分子化合物选自环糊精或合成环糊精及其衍生物。本发明的美洛昔康组合物不合有任何有机溶剂，能有效避免药物制剂不良反应的产生，使药物使用更为安全，同时也降低了药物在制备过程中对环境的污染。