Nanocrystalline preparation of ROCK2 inhibitor and preparation method thereof
The invention discloses a nanocrystal preparation and a preparation method thereof. The nanocrystal preparation comprises a ROCK2 inhibitor and a stabilizer. The invention also relates to application of the nanocrystalline preparation in preventing, relieving and/or treating selected diseases and me...
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| creator | ZHANG ZHIBING XU JIAJIA LU DI LU YONGJIE NIU SHENGPAN ZHANG SHASHA ZHU CHAOLU |
| description | The invention discloses a nanocrystal preparation and a preparation method thereof. The nanocrystal preparation comprises a ROCK2 inhibitor and a stabilizer. The invention also relates to application of the nanocrystalline preparation in preventing, relieving and/or treating selected diseases and medical diseases, especially diseases such as idiopathic pulmonary fibrosis, fatty liver diseases and/or steatohepatitis, graft versus host diseases after hematopoietic stem cell transplantation or virus infection.
一种纳米晶制剂及其制备方法，所述纳米晶制剂包含ROCK2抑制剂和稳定剂。还涉及所述纳米晶制剂在用于预防、缓解和/或治疗所选疾病及医学病症，尤其是特发性肺纤维化、脂肪性肝病和/或脂肪性肝炎、造血干细胞移植后的移植物抗宿主病或者病毒感染等疾病中的用途。 |
| format | Patent |
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一种纳米晶制剂及其制备方法，所述纳米晶制剂包含ROCK2抑制剂和稳定剂。还涉及所述纳米晶制剂在用于预防、缓解和/或治疗所选疾病及医学病症，尤其是特发性肺纤维化、脂肪性肝病和/或脂肪性肝炎、造血干细胞移植后的移植物抗宿主病或者病毒感染等疾病中的用途。</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240618&DB=EPODOC&CC=CN&NR=118215468A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240618&DB=EPODOC&CC=CN&NR=118215468A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHANG ZHIBING</creatorcontrib><creatorcontrib>XU JIAJIA</creatorcontrib><creatorcontrib>LU DI</creatorcontrib><creatorcontrib>LU YONGJIE</creatorcontrib><creatorcontrib>NIU SHENGPAN</creatorcontrib><creatorcontrib>ZHANG SHASHA</creatorcontrib><creatorcontrib>ZHU CHAOLU</creatorcontrib><title>Nanocrystalline preparation of ROCK2 inhibitor and preparation method thereof</title><description>The invention discloses a nanocrystal preparation and a preparation method thereof. The nanocrystal preparation comprises a ROCK2 inhibitor and a stabilizer. The invention also relates to application of the nanocrystalline preparation in preventing, relieving and/or treating selected diseases and medical diseases, especially diseases such as idiopathic pulmonary fibrosis, fatty liver diseases and/or steatohepatitis, graft versus host diseases after hematopoietic stem cell transplantation or virus infection.
一种纳米晶制剂及其制备方法，所述纳米晶制剂包含ROCK2抑制剂和稳定剂。还涉及所述纳米晶制剂在用于预防、缓解和/或治疗所选疾病及医学病症，尤其是特发性肺纤维化、脂肪性肝病和/或脂肪性肝炎、造血干细胞移植后的移植物抗宿主病或者病毒感染等疾病中的用途。</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPD1S8zLTy6qLC5JzMnJzEtVKChKLUgsSizJzM9TyE9TCPJ39jZSyMzLyEzKLMkvUkjMS0FRkptakpGfolCSkVqUmp_Gw8CalphTnMoLpbkZFN1cQ5w9dFML8uNTiwsSk1PzUkvinf0MDS2MDE1NzCwcjYlRAwDzDjZb</recordid><startdate>20240618</startdate><enddate>20240618</enddate><creator>ZHANG ZHIBING</creator><creator>XU JIAJIA</creator><creator>LU DI</creator><creator>LU YONGJIE</creator><creator>NIU SHENGPAN</creator><creator>ZHANG SHASHA</creator><creator>ZHU CHAOLU</creator><scope>EVB</scope></search><sort><creationdate>20240618</creationdate><title>Nanocrystalline preparation of ROCK2 inhibitor and preparation method thereof</title><author>ZHANG ZHIBING ; XU JIAJIA ; LU DI ; LU YONGJIE ; NIU SHENGPAN ; ZHANG SHASHA ; ZHU CHAOLU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN118215468A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHANG ZHIBING</creatorcontrib><creatorcontrib>XU JIAJIA</creatorcontrib><creatorcontrib>LU DI</creatorcontrib><creatorcontrib>LU YONGJIE</creatorcontrib><creatorcontrib>NIU SHENGPAN</creatorcontrib><creatorcontrib>ZHANG SHASHA</creatorcontrib><creatorcontrib>ZHU CHAOLU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHANG ZHIBING</au><au>XU JIAJIA</au><au>LU DI</au><au>LU YONGJIE</au><au>NIU SHENGPAN</au><au>ZHANG SHASHA</au><au>ZHU CHAOLU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Nanocrystalline preparation of ROCK2 inhibitor and preparation method thereof</title><date>2024-06-18</date><risdate>2024</risdate><abstract>The invention discloses a nanocrystal preparation and a preparation method thereof. The nanocrystal preparation comprises a ROCK2 inhibitor and a stabilizer. The invention also relates to application of the nanocrystalline preparation in preventing, relieving and/or treating selected diseases and medical diseases, especially diseases such as idiopathic pulmonary fibrosis, fatty liver diseases and/or steatohepatitis, graft versus host diseases after hematopoietic stem cell transplantation or virus infection.
一种纳米晶制剂及其制备方法，所述纳米晶制剂包含ROCK2抑制剂和稳定剂。还涉及所述纳米晶制剂在用于预防、缓解和/或治疗所选疾病及医学病症，尤其是特发性肺纤维化、脂肪性肝病和/或脂肪性肝炎、造血干细胞移植后的移植物抗宿主病或者病毒感染等疾病中的用途。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Nanocrystalline preparation of ROCK2 inhibitor and preparation method thereof |
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