Preparation method and application of aflatoxin A nanoemulsion

The invention relates to the technical field of medicines, in particular to preparation and application of aflatoxin A nanoemulsion. The specific technical scheme is as follows: the preparation method of the aflatoxin A nanoemulsion comprises the following steps: mixing and stirring aflatoxin A, an...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: YE XINGCHEN, XIE QINGCHUN, LI YONG, WANG JIU, LIU YING, SI YUAN, HUANG YONGTONG, BAI NINGNING
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to the technical field of medicines, in particular to preparation and application of aflatoxin A nanoemulsion. The specific technical scheme is as follows: the preparation method of the aflatoxin A nanoemulsion comprises the following steps: mixing and stirring aflatoxin A, an oil phase and a composite surfactant until the aflatoxin A is dissolved, slowly dropwise adding water, and stirring until the emulsion is clear, transparent and blue-light, thereby obtaining the aflatoxin A nanoemulsion. According to the invention, the problems of poor water solubility, low oral bioavailability and the like of the aflatoxin A in the prior art are solved. 本发明涉及医药技术领域,具体涉及一种黄花香茶菜甲素纳米乳的制备及应用。具体技术方案为:一种黄花香茶菜甲素纳米乳的制备方法,将黄花香茶菜甲素与油相和复合表面活性剂混合搅拌至黄花香茶菜甲素溶解后,缓慢滴加水,搅拌至乳液澄清透明泛蓝光即得黄花香茶菜甲素纳米乳。本发明解决了现有技术中黄花香茶菜甲素水溶性差、口服生物利用度低等问题。