Inhalated iloprost for on-demand treatment of pulmonary arterial hypertension

Provided herein are methods of treating pulmonary arterial hypertension. The method comprises administering to the subject an effective amount of iloprost as needed or as a rescue drug (also referred to as needed, PRN) wherein iloprost is administered to the subject by inhalation using a portable so...

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Hauptverfasser: SEGER WERNER, GEISSLER TOBIAS
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided herein are methods of treating pulmonary arterial hypertension. The method comprises administering to the subject an effective amount of iloprost as needed or as a rescue drug (also referred to as needed, PRN) wherein iloprost is administered to the subject by inhalation using a portable soft mist inhaler. In a preferred embodiment, the soft mist inhaler is a Responmatt TM or Medspray TM wet aerosol inhaler. A method of treating a patient suffering from pulmonary arterial hypertension, the method comprising: (a) providing a portable, pre-filled soft mist inhaler adapted to deliver an effective amount of iloprost; and (b) administering an effective amount of iloprost to the patient as desired by inhalation. 本文提供了治疗肺动脉高压的方法。该方法包括根据需要或作为救援药物(也称为需要时,PRN)向受试者给药有效量的伊洛前列素,其中使用便携式软雾吸入器通过吸入向受试者给药伊洛前列素。在优选的实施方式中,软雾吸入器是RespimatTM或MedsprayTM湿气雾剂吸入器。一种治疗患有肺动脉高压患者的方法,该方法包括:(a)提供适合递送有效量的伊洛前列素的便携式、预填充的软雾吸入器;和(b)根据需要通过吸入向患者给药有效量的伊洛前列素。