Zirconium porphyrin metal organic framework nano-enzyme as well as preparation method and application thereof

The invention relates to a nano biological material, in particular to zirconium porphyrin metal organic framework nano enzyme as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing MESO-tetra (4-carboxyphenyl) porphin, zirconium tetrachl...

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Bibliographische Detailangaben
Hauptverfasser:	HUANG XIAOLIN, LI QIANYING, TAN XINLIU, XIONG YONGHUA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MANUFACTURE OR TREATMENT OF NANOSTRUCTURES MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES MEDICAL OR VETERINARY SCIENCE METALLURGY NANOTECHNOLOGY ORGANIC MACROMOLECULAR COMPOUNDS PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES THEIR PREPARATION OR CHEMICAL WORKING-UP THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	The invention relates to a nano biological material, in particular to zirconium porphyrin metal organic framework nano enzyme as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing MESO-tetra (4-carboxyphenyl) porphin, zirconium tetrachloride, aryl dicarboxylic acid and a morphology regulator in a first solvent, reacting at 120-140 DEG C, washing and separating precipitate to obtain a zirconium porphyrin metal organic framework material; and dispersing the zirconium porphyrin metal organic framework material in a second solvent, adding a metal precursor solution, reacting at 80-90 DEG C, washing, separating and precipitating to obtain the zirconium porphyrin metal organic framework nano-enzyme. The zirconium porphyrin metal organic framework nano-enzyme has good peroxidase activity and can be used for preparing drugs or auxiliary materials for resisting bacterial infection or preventing and treating biological membranes. 本发明涉及纳米生物材料，具体涉及锆卟啉金属有机框架纳