Application of chemotactic factor XCL1 in preparation of medicine for resisting advanced pregnant woman late stage bad pregnancy outcome

The invention discloses application of a chemotactic factor XCL1 in preparation of a medicine for resisting advanced pregnant woman late-stage bad pregnancy outcome. The invention discloses an application of a chemotactic factor XCL1 in resisting an adverse pregnancy outcome of an elderly pregnant woman, and particularly, the chemotactic factor XCL1 improves the growth limitation of a fetus and plays an important role in the pregnancy process. By applying the XCL1 recombinant protein, the phenotype of fetal growth limitation of the elderly pregnant rats can be relieved, the possibility of occurrence of bad pregnancy outcome is reduced, and a new effective measure is provided for clinically treating late bad pregnancy outcome of the elderly pregnant women. 本发明公开了趋化因子XCL1在制备抗高龄孕妇晚期不良妊娠结局药物中的应用。本发明公开了趋化因子XCL1在抗高龄孕妇不良妊娠结局中的应用，尤其是趋化因子XCL1改善了胎儿生长受限，其在妊娠过程中有重要作用。通过施加XCL1重组蛋白能缓解高龄孕鼠胎儿生长受限的表型，降低了出现不良妊娠结局的可能，为临床上治疗高龄孕妇晚期不良妊娠结局的道路上提供一个新的有效措施。