Method for treating macrophage damage caused by sepsis important medium

The invention provides a method for treating macrophage damage caused by a sepsis important medium. Components capable of providing magnesium ions are used for preparing a preparation for preventing and treating cell damage. As a specific record of the embodiment, the cell injury is macrophage injury caused by an important medium of sepsis. The method provided by the invention can improve mitochondrial-related apoptosis and bacterial phagocytic dysfunction of macrophages caused by circulating histone generated by sepsis, and it can be known from a mouse model that Mg < 2 + > can relieve histone-induced macrophage apoptosis and bacterial phagocytic dysfunction, reduce in-vivo bacterial load and improve the survival rate of histone-stimulated mice. Therefore, Mg < 2 + > can be used as a targeted drug for treating extracellular histone mediated macrophage damage caused by sepsis. 本发明提供一种治疗脓毒症重要介质引起的巨噬细胞损伤的方法，是使用能提供镁离子的组分来制备用于预防治疗细胞损伤的制剂。所述的细胞损伤，作为实施例的具体记载，是脓毒症重要介质引起的巨噬细胞损伤。本发明所提供的方法可改善脓毒症产生的循环组蛋白导致巨噬细胞的线粒体相关性凋亡和