Quaternary ammonium salt oxazolidinone derivative as well as medicinal salt, preparation method and application thereof

The invention belongs to the technical field of medicine synthesis, and particularly relates to a quaternary ammonium salt oxazolidinone derivative and a medicinal salt, a preparation method and application thereof. The quaternary ammonium salt oxazolidinone derivative and the pharmaceutical salt thereof provided by the invention are excellent in antibacterial activity and relatively low in cytotoxicity, and can be used for inhibiting the combination of formylmethionine tRNA and a ribosome peptidyl transferase central P site by acting on 23S rRNA of a bacterial ribosome 50S subunit, and preventing the formation of a formylmethionine tRNA, ribosome and mRNA ternary complex, namely a 70S initial complex, so that the antibacterial activity of the quaternary ammonium salt oxazolidinone derivative is improved. Therefore, the synthesis of the bacterial protein stops at the initial stage, the problem of cross resistance with other existing antibiotics is avoided, and the bacterial protein can be used for preparing g