Anti-Siglec-15 antibody and application thereof

The invention provides an anti-Siglec-15 antibody and an application thereof. Specifically, provided are a separated anti-Siglec-15 antibody or an antigen-binding fragment thereof, an expression vector and a host cell for expressing the antibody or the antigen-binding fragment thereof, and an application of the antibody or the antigen-binding fragment. Further provided are pharmaceutical compositions containing the aforementioned antibodies or antigen-binding fragments thereof, and uses of the aforementioned pharmaceutical compositions. 提供了抗Siglec-15抗体及其应用。具体来说，提供了分离的抗Siglec-15抗体或其抗原结合片段，用于表达前述抗体或其抗原结合片段的表达载体和宿主细胞，以及前述抗体或者抗原结合片段的应用。进一步提供了含有前述抗体或其抗原结合片段的药物组合物，以及前述药物组合物的应用。