Activator of bone morphogenetic protein-2 and application thereof

The invention relates to the field of stem cells, in particular to a bone morphogenetic protein-2 activator and application thereof. The activating agent of the bone morphogenetic protein-2 is levistilide A. The invention further discloses a preparation method of the bone morphogenetic protein-2. The inventor team concludes, analyzes and summarizes a large amount of test data in the early stage to find that the activator levistilide A of the bone morphogenetic protein-2 has good biocompatibility, and the levistilide A can promote the expression of BMP-2 protein in bone marrow mesenchymal stem cells. Based on the theoretical basis, the inventor team creatively adds levistilide A into the culture medium for osteogenic induced differentiation of the bone marrow mesenchymal stem cells, and the osteogenic differentiation degree of the bone marrow mesenchymal stem cells is remarkably improved. 本发明涉及干细胞领域，尤其涉及一种骨形态发生蛋白-2的激活剂及其应用。该骨形态发生蛋白-2的激活剂为欧当归内酯A。本发明人团队通过对前期大量试验数据进行归纳、分析、总结发现：骨形态发生蛋白-2的激活剂欧当归内酯A具有良好的生物相容性，且欧当归内酯