Anti-sclerostatin constructs and uses thereof

Provided herein are anti-sclerostatin molecules that bind to sclerostatin (e.g., anti-sclerostatin antibodies, e.g., anti-sclerostatin antibodies, e.g., anti-sclerostatin antibodies). The invention relates to an anti-sclerostatin construct (e.g., a bispecific anti-sclerostatin antibody), a nucleic acid molecule encoding an anti-sclerostatin amino acid sequence, a carrier containing the nucleic acid molecule, a host cell containing the carrier, a preparation method of the anti-sclerostatin construct, a pharmaceutical composition containing the anti-sclerostatin construct, and a use method of the anti-sclerostatin construct or composition. 本申请提供了与硬骨抑素结合的抗硬骨抑素分子(例如，抗硬骨抑素抗体，例如，双特异性抗硬骨抑素抗体)、编码抗硬骨抑素氨基酸序列的核酸分子、包含该核酸分子的载体、含有该载体的宿主细胞、抗硬骨抑素构建体的制备方法、含有抗硬骨抑素构建体的药物组合物以及抗硬骨抑素构建体或组合物的使用方法。