Anti-human LAG3 nano antibody as well as preparation method and application thereof

The invention provides a nano antibody specifically combined with human LAG3 protein as well as a preparation method and application of the nano antibody. The nano antibody disclosed by the invention is good in homogeneity, high in purity and high in thermal stability, has high specificity and high...

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Bibliographische Detailangaben
Hauptverfasser: LI QING, CHEN YUEWEN, YAN FENGYING, WU WEIDANG, YANG ZIWEI, WEN RUIXIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a nano antibody specifically combined with human LAG3 protein as well as a preparation method and application of the nano antibody. The nano antibody disclosed by the invention is good in homogeneity, high in purity and high in thermal stability, has high specificity and high affinity to human LAG3 protein, and can be used for diagnosing and/or treating LAG3 related diseases, such as diagnosis and/or treatment of human tumors. 本发明提供了一种特异性结合人LAG3蛋白的纳米抗体及其制备方法和用途。本发明的纳米抗体均一性好,纯度高,热稳定性高,对人LAG3蛋白具有高特异性和高亲和性,能够用于诊断和/或治疗LAG3相关疾病,例如人肿瘤的诊断和/或治疗。