Sesquiterpenoids oxyphyllGuane F separated from fructus alpiniae oxyphyllae and application of sesquiterpenoids oxyphyllGuane F

The invention relates to a sesquiterpene compound oxyphyllane F separated from fructus alpiniae oxyphyllae and application of the sesquiterpene compound oxyphyllane F, a compound with a novel structure is found in the fructus alpiniae oxyphyllae, application of a new compound in development of a kidney protection medicine is achieved, and the technical scheme for solving the problem is that the new sesquiterpene compound oxyphyllane F is separated and identified from an n-butyl alcohol part of the fructus alpiniae oxyphyllae, and the new compound oxyphyllane F can be used for preparing a kidney protection medicine. The compound can inhibit and weaken expression of fibronectin, I-type collagen and alpha-SMA in rat renal tubular duct epithelial cells induced by TGF-beta1 in a dose-dependent manner, has anti-renal fibrosis activity and can be effectively used for preparing renal protection drugs, the preparation method of the compound has good reproducibility, and the obtained compound is high in purity and suit