Peptide and protein interaction and corresponding binding residue prediction method and system
The invention discloses a prediction method for peptide-protein interaction and corresponding binding residues. The prediction method comprises the following steps: acquiring peptide-protein interaction and corresponding interaction site information, and constructing a data set; calculating the mult...
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| creator | ZHAO HAOCHEN WANG JIANXIN ZHOU RUIKANG DUAN GUIHUA |
| description | The invention discloses a prediction method for peptide-protein interaction and corresponding binding residues. The prediction method comprises the following steps: acquiring peptide-protein interaction and corresponding interaction site information, and constructing a data set; calculating the multi-source sequence characteristics of the peptide and the protein; constructing peptide residue features, protein residue features, peptide sequence features and protein sequence features, and mapping the features to a unified feature dimension space to obtain corresponding feature vectors; constructing a peptide-protein pair interaction diagram; constructing a peptide and protein interaction and corresponding binding site prediction model, and training; and adopting the trained peptide and protein interaction and corresponding binding site prediction model to predict the actual peptide-protein interaction result and the interaction residue site. The invention also discloses a system for realizing the method for pre |
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| subjects | CALCULATING COMPUTER SYSTEMS BASED ON SPECIFIC COMPUTATIONAL MODELS COMPUTING COUNTING ELECTRIC DIGITAL DATA PROCESSING INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS PHYSICS |
| title | Peptide and protein interaction and corresponding binding residue prediction method and system |
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