Liquid chromatography-mass spectrometry detection method for 14 vertigo syncope and stroke drugs in blood

The invention provides application of a reagent for detecting a target compound combination in preparation of a detection agent, and the detection agent is used for screening and identifying whether a tested object takes drugs for treating dizziness, syncope or cerebral apoplexy or not and assisting...

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Bibliographische Detailangaben
Hauptverfasser: WANG WEI, LI BOYE, JI ENHUI, XU WEIZHE, YU HONGYAN, LI QINGYAN, XU HAISHAN, GUO DANMING, LIU YONGSUO, QIAO SHI, CUI YUJING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides application of a reagent for detecting a target compound combination in preparation of a detection agent, and the detection agent is used for screening and identifying whether a tested object takes drugs for treating dizziness, syncope or cerebral apoplexy or not and assisting in judging whether the tested object suffers from related diseases or not. Wherein the target compound combination comprises one, a plurality of or all of lidocaine, cinepazide, ticlopidine, pentobutalol, fendilin, cinnarizine, clopidogrel, midodrine, dipyridamole, argatroban, rosuvastatin, atorvastatin, fluvastatin and pitavastatin. The plasma sample pretreatment method is simple, short in detection and analysis time, high in sensitivity and large in detection variety and quantity; the method is divided into a preliminary screening method and a re-checking method, the accuracy of a detection result can be improved, and false negative and false positive results are avoided. 本发明提供了一种检测目标化合物组合的试剂在制备检测剂中的用途,所述检测剂用于筛查