Avian escherichia coli O145 serotype inactivated vaccine and preparation method thereof

The invention provides an avian escherichia coli O145 serotype inactivated vaccine and a preparation method thereof. The avian escherichia coli disclosed by the invention is Escherichia coli JX164, the preservation number is CCTCC (China Center For Type Culture Collection) NO: M 20231988, and the avian escherichia coli can be used for preparing an avian escherichia coli O145 serotype inactivated vaccine; after standing for 12 hours, the avian escherichia coli O145 serotype inactivated vaccine disclosed by the invention is uniformly distributed and has no layering phenomenon; within 7 days after immunization, each group of ducks does not have obvious side reaction, the survival rate of 7 days after immunization reaches 100%, and good safety is achieved; the avian Escherichia coli O145 inactivated vaccine prepared by the invention can resist infection of same serotype virulent strains, provides a higher protection rate, but has a lower cross protection rate. 本发明提供了一种禽大肠杆菌O145血清型灭活疫苗及其制备方法。本发明的禽大肠杆菌为大肠埃希氏菌(Esche