Fused bicyclic heteroaryl compounds as NLRP3 inhibitors
The present invention relates to novel compounds having the general formula Ic, # imgabs0 # wherein R1, R2, R3, R8, R9, RX, A1, A2, W and n are as described herein; compositions comprising the compounds; and methods of using the compounds. 本发明涉及具有通式Ic的新颖化合物，#imgabs0#其中R1、R2、R3、R8、R9、RX、A1、A2、W和n如本文所...
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| creator | GUBA, WOLFGANG AITKEN LINDA SUE SHANNON JONATHAN MARTIN PATINY-ADAM, ANDR JAESCHKE GEORG JOHNSTON, H., JOHN MESCH, SCOTT, K SCHNIEDER CHRISTIAN STEINER SANDRA TOSTOV ALEXANDER MIKHAILOVICH BUSH LAWRENCE A |
| description | The present invention relates to novel compounds having the general formula Ic, # imgabs0 # wherein R1, R2, R3, R8, R9, RX, A1, A2, W and n are as described herein; compositions comprising the compounds; and methods of using the compounds.
本发明涉及具有通式Ic的新颖化合物，#imgabs0#其中R1、R2、R3、R8、R9、RX、A1、A2、W和n如本文所述；包含所述化合物的组合物；以及使用所述化合物的方法。 |
| format | Patent |
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本发明涉及具有通式Ic的新颖化合物，#imgabs0#其中R1、R2、R3、R8、R9、RX、A1、A2、W和n如本文所述；包含所述化合物的组合物；以及使用所述化合物的方法。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240531&DB=EPODOC&CC=CN&NR=118119626A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240531&DB=EPODOC&CC=CN&NR=118119626A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GUBA, WOLFGANG</creatorcontrib><creatorcontrib>AITKEN LINDA SUE</creatorcontrib><creatorcontrib>SHANNON JONATHAN MARTIN</creatorcontrib><creatorcontrib>PATINY-ADAM, ANDR</creatorcontrib><creatorcontrib>JAESCHKE GEORG</creatorcontrib><creatorcontrib>JOHNSTON, H., JOHN</creatorcontrib><creatorcontrib>MESCH, SCOTT, K</creatorcontrib><creatorcontrib>SCHNIEDER CHRISTIAN</creatorcontrib><creatorcontrib>STEINER SANDRA</creatorcontrib><creatorcontrib>TOSTOV ALEXANDER MIKHAILOVICH</creatorcontrib><creatorcontrib>BUSH LAWRENCE A</creatorcontrib><title>Fused bicyclic heteroaryl compounds as NLRP3 inhibitors</title><description>The present invention relates to novel compounds having the general formula Ic, # imgabs0 # wherein R1, R2, R3, R8, R9, RX, A1, A2, W and n are as described herein; compositions comprising the compounds; and methods of using the compounds.
本发明涉及具有通式Ic的新颖化合物，#imgabs0#其中R1、R2、R3、R8、R9、RX、A1、A2、W和n如本文所述；包含所述化合物的组合物；以及使用所述化合物的方法。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB3Ky1OTVFIykyuTM7JTFbISC1JLcpPLKrMUUjOzy3IL81LKVZILFbw8wkKMFbIzMvITMosyS8q5mFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8c5-hoYWhoaWZkZmjsbEqAEAu60tsg</recordid><startdate>20240531</startdate><enddate>20240531</enddate><creator>GUBA, WOLFGANG</creator><creator>AITKEN LINDA SUE</creator><creator>SHANNON JONATHAN MARTIN</creator><creator>PATINY-ADAM, ANDR</creator><creator>JAESCHKE GEORG</creator><creator>JOHNSTON, H., JOHN</creator><creator>MESCH, SCOTT, K</creator><creator>SCHNIEDER CHRISTIAN</creator><creator>STEINER SANDRA</creator><creator>TOSTOV ALEXANDER MIKHAILOVICH</creator><creator>BUSH LAWRENCE A</creator><scope>EVB</scope></search><sort><creationdate>20240531</creationdate><title>Fused bicyclic heteroaryl compounds as NLRP3 inhibitors</title><author>GUBA, WOLFGANG ; AITKEN LINDA SUE ; SHANNON JONATHAN MARTIN ; PATINY-ADAM, ANDR ; JAESCHKE GEORG ; JOHNSTON, H., JOHN ; MESCH, SCOTT, K ; SCHNIEDER CHRISTIAN ; STEINER SANDRA ; TOSTOV ALEXANDER MIKHAILOVICH ; BUSH LAWRENCE A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN118119626A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GUBA, WOLFGANG</creatorcontrib><creatorcontrib>AITKEN LINDA SUE</creatorcontrib><creatorcontrib>SHANNON JONATHAN MARTIN</creatorcontrib><creatorcontrib>PATINY-ADAM, ANDR</creatorcontrib><creatorcontrib>JAESCHKE GEORG</creatorcontrib><creatorcontrib>JOHNSTON, H., JOHN</creatorcontrib><creatorcontrib>MESCH, SCOTT, K</creatorcontrib><creatorcontrib>SCHNIEDER CHRISTIAN</creatorcontrib><creatorcontrib>STEINER SANDRA</creatorcontrib><creatorcontrib>TOSTOV ALEXANDER MIKHAILOVICH</creatorcontrib><creatorcontrib>BUSH LAWRENCE A</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GUBA, WOLFGANG</au><au>AITKEN LINDA SUE</au><au>SHANNON JONATHAN MARTIN</au><au>PATINY-ADAM, ANDR</au><au>JAESCHKE GEORG</au><au>JOHNSTON, H., JOHN</au><au>MESCH, SCOTT, K</au><au>SCHNIEDER CHRISTIAN</au><au>STEINER SANDRA</au><au>TOSTOV ALEXANDER MIKHAILOVICH</au><au>BUSH LAWRENCE A</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Fused bicyclic heteroaryl compounds as NLRP3 inhibitors</title><date>2024-05-31</date><risdate>2024</risdate><abstract>The present invention relates to novel compounds having the general formula Ic, # imgabs0 # wherein R1, R2, R3, R8, R9, RX, A1, A2, W and n are as described herein; compositions comprising the compounds; and methods of using the compounds.
本发明涉及具有通式Ic的新颖化合物，#imgabs0#其中R1、R2、R3、R8、R9、RX、A1、A2、W和n如本文所述；包含所述化合物的组合物；以及使用所述化合物的方法。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Fused bicyclic heteroaryl compounds as NLRP3 inhibitors |
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