Fused bicyclic heteroaryl compounds as NLRP3 inhibitors

The present invention relates to novel compounds having the general formula Ic, # imgabs0 # wherein R1, R2, R3, R8, R9, RX, A1, A2, W and n are as described herein; compositions comprising the compounds; and methods of using the compounds. 本发明涉及具有通式Ic的新颖化合物,#imgabs0#其中R1、R2、R3、R8、R9、RX、A1、A2、W和n如本文所...

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Hauptverfasser: GUBA, WOLFGANG, AITKEN LINDA SUE, SHANNON JONATHAN MARTIN, PATINY-ADAM, ANDR, JAESCHKE GEORG, JOHNSTON, H., JOHN, MESCH, SCOTT, K, SCHNIEDER CHRISTIAN, STEINER SANDRA, TOSTOV ALEXANDER MIKHAILOVICH, BUSH LAWRENCE A
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to novel compounds having the general formula Ic, # imgabs0 # wherein R1, R2, R3, R8, R9, RX, A1, A2, W and n are as described herein; compositions comprising the compounds; and methods of using the compounds. 本发明涉及具有通式Ic的新颖化合物,#imgabs0#其中R1、R2、R3、R8、R9、RX、A1、A2、W和n如本文所述;包含所述化合物的组合物;以及使用所述化合物的方法。