Lipid quality control product as well as preparation method and application thereof

The invention discloses a lipid quality control product as well as a preparation method and application thereof. The lipid quality control product is in a freeze-drying dosage form and comprises a matrix liquid and a lipid marker, the matrix liquid comprises a matrix, a pH buffering agent, a filling...

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Bibliographische Detailangaben
Hauptverfasser: WANG BOWEI, ZHAO JIANGMAN, LIN LING, LYU FANG, LOU JINGWEI, QI JIACHEN, WANG MENGZHU
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a lipid quality control product as well as a preparation method and application thereof. The lipid quality control product is in a freeze-drying dosage form and comprises a matrix liquid and a lipid marker, the matrix liquid comprises a matrix, a pH buffering agent, a filling agent, an excipient and a macromolecular protective agent; the lipid marker comprises a low-density lipid protein. The lipid quality control product provided by the invention has good long-term storage stability and stability after redissolution, has a shelf life of 6 months at 2-8 DEG C, and is suitable for quality control of serum or plasma sample lipoprotein accurate fine classification detection. 本发明公开了一种脂类质控品及其制备方法和应用。所述脂类质控品为冻干剂型,所述脂类质控品包括:基质液和脂类标志物;所述基质液包括基质、pH缓冲剂、填充剂、赋性剂和高分子保护剂;所述脂类标志物包括低密度脂蛋白质。本发明所述脂类质控品的长期储存稳定性及复溶后稳定性良好,2~8℃下保存有效期为6个月,适用于血清或血浆样本脂蛋白精确细分类检测的质量控制。