Synthesis method of substituted benzoyl isocyanate
The invention discloses a synthetic method of substituted benzoyl isocyanate, and belongs to the technical field of synthesis of pesticide intermediates, the synthetic method comprises the following steps: adding sodium cyanate and a composite catalyst into an organic solvent, heating to 40-60 DEG C...
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creator | WANG ZHENYU CHEN JUKUI ZHU ZHANG ZHANG JUN LI JIAN JIANG JINGWEN SU RUI |
description | The invention discloses a synthetic method of substituted benzoyl isocyanate, and belongs to the technical field of synthesis of pesticide intermediates, the synthetic method comprises the following steps: adding sodium cyanate and a composite catalyst into an organic solvent, heating to 40-60 DEG C, dropwise adding benzoyl chloride into the organic solvent, heating to 60 DEG C after dropwise adding, stirring at a constant temperature for 3.2-5.5 h, cooling to the room temperature, and filtering to obtain the substituted benzoyl isocyanate. And after the reaction is finished, distilling off the solvent under reduced pressure, and continuously distilling off the substituted benzoyl isocyanate under reduced pressure. Under the composite catalytic action of p-toluenesulfonic acid and heteropoly acid, the purpose of increasing the yield of substituted benzoyl isocyanate is finally achieved, through inspection, the yield reaches 92.5%-95.0%, meanwhile, the reaction efficiency is remarkably improved, finally, effic |
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And after the reaction is finished, distilling off the solvent under reduced pressure, and continuously distilling off the substituted benzoyl isocyanate under reduced pressure. 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And after the reaction is finished, distilling off the solvent under reduced pressure, and continuously distilling off the substituted benzoyl isocyanate under reduced pressure. Under the composite catalytic action of p-toluenesulfonic acid and heteropoly acid, the purpose of increasing the yield of substituted benzoyl isocyanate is finally achieved, through inspection, the yield reaches 92.5%-95.0%, meanwhile, the reaction efficiency is remarkably improved, finally, effic</abstract><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING |
title | Synthesis method of substituted benzoyl isocyanate |
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