Synthesis method of substituted benzoyl isocyanate
The invention discloses a synthetic method of substituted benzoyl isocyanate, and belongs to the technical field of synthesis of pesticide intermediates, the synthetic method comprises the following steps: adding sodium cyanate and a composite catalyst into an organic solvent, heating to 40-60 DEG C...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a synthetic method of substituted benzoyl isocyanate, and belongs to the technical field of synthesis of pesticide intermediates, the synthetic method comprises the following steps: adding sodium cyanate and a composite catalyst into an organic solvent, heating to 40-60 DEG C, dropwise adding benzoyl chloride into the organic solvent, heating to 60 DEG C after dropwise adding, stirring at a constant temperature for 3.2-5.5 h, cooling to the room temperature, and filtering to obtain the substituted benzoyl isocyanate. And after the reaction is finished, distilling off the solvent under reduced pressure, and continuously distilling off the substituted benzoyl isocyanate under reduced pressure. Under the composite catalytic action of p-toluenesulfonic acid and heteropoly acid, the purpose of increasing the yield of substituted benzoyl isocyanate is finally achieved, through inspection, the yield reaches 92.5%-95.0%, meanwhile, the reaction efficiency is remarkably improved, finally, effic |
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