Bacillus subtilis mutant strain for producing adenosine as well as fermentation process and application of bacillus subtilis mutant strain
The invention discloses a bacillus subtilis mutant strain for producing adenosine as well as a fermentation process and application thereof, and belongs to the technical field of genetic engineering. In order to solve the technical problems that in the prior art, a chemical synthesis method for prod...
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| creator | YU DESHUI LIU WEI YAN GENGXUAN ZHANG YUNZHI ZHANG SHUMEI TIAN YUAN REN HONGFA |
| description | The invention discloses a bacillus subtilis mutant strain for producing adenosine as well as a fermentation process and application thereof, and belongs to the technical field of genetic engineering. In order to solve the technical problems that in the prior art, a chemical synthesis method for producing adenosine is complex in process, high in cost and low in extraction rate, the invention provides a bacillus subtilis mutant strain for highly producing adenosine and a fermentation process and application of the bacillus subtilis mutant strain. An HW9801 mutant strain with high adenosine yield is obtained, a fermentation process for producing adenosine is optimized through single factor and response surface tests, and an optimal fermentation process is determined; according to the mutant strain provided by the invention, the adenosine yield is increased by 2.58 times, and compared with a traditional fermentation process, the adenosine yield is increased by 2.88 times through an optimized fermentation process; |
| format | Patent |
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An HW9801 mutant strain with high adenosine yield is obtained, a fermentation process for producing adenosine is optimized through single factor and response surface tests, and an optimal fermentation process is determined; according to the mutant strain provided by the invention, the adenosine yield is increased by 2.58 times, and compared with a traditional fermentation process, the adenosine yield is increased by 2.88 times through an optimized fermentation process;</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240528&DB=EPODOC&CC=CN&NR=118086127A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240528&DB=EPODOC&CC=CN&NR=118086127A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YU DESHUI</creatorcontrib><creatorcontrib>LIU WEI</creatorcontrib><creatorcontrib>YAN GENGXUAN</creatorcontrib><creatorcontrib>ZHANG YUNZHI</creatorcontrib><creatorcontrib>ZHANG SHUMEI</creatorcontrib><creatorcontrib>TIAN YUAN</creatorcontrib><creatorcontrib>REN HONGFA</creatorcontrib><title>Bacillus subtilis mutant strain for producing adenosine as well as fermentation process and application of bacillus subtilis mutant strain</title><description>The invention discloses a bacillus subtilis mutant strain for producing adenosine as well as a fermentation process and application thereof, and belongs to the technical field of genetic engineering. 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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Bacillus subtilis mutant strain for producing adenosine as well as fermentation process and application of bacillus subtilis mutant strain |
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