Production process of 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone

The invention discloses a production process of 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone, and the production process of the 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone comprises the following steps: mixing 1-(4-chlorphenyl)-4, 4-dimethyl-1-ene-3-pentanone with potassium hydroxide, adding a cataly...

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Bibliographische Detailangaben
Hauptverfasser: LI SHOUFENG, CHENG WEI, GE XINFANG, YANG FENGKE, TIAN DASHUAI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a production process of 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone, and the production process of the 1-(4-chlorphenyl)-4, 4-dimethyl-3-pentanone comprises the following steps: mixing 1-(4-chlorphenyl)-4, 4-dimethyl-1-ene-3-pentanone with potassium hydroxide, adding a catalyst, stirring, and reacting at the temperature of 60-80 DEG C to obtain the 1-(4-chlorphenyl)-4, 4-dimethyl-1-ene-3-pentanone. Then adding a composite sulfide composed of a Raney nickel catalyst, dimethyl sulfoxide and 2-hydroxyethyl disulfide as a cocatalyst, introducing hydrogen at 90-95 DEG C, controlling the hydrogen pressure to be 0.5-0.6 MPa, carrying out a first-stage reaction, after the first-stage reaction is finished, reducing the reaction temperature to 70-75 DEG C, increasing the hydrogen pressure to 1.1-1.3 MPa, carrying out a second-stage reaction, after the reaction is finished, carrying out a second-stage reaction, and after the second-stage reaction is finished, carrying out a third-stage reaction;