Composite collagen-based wound dressing containing rare earth ions and preparation method thereof

The invention provides a composite collagen-based wound dressing containing rare earth ions and a preparation method of the composite collagen-based wound dressing. The composite collagen-based wound dressing containing the rare earth ions is prepared by taking collagen, polysaccharide and a rare ea...

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Bibliographische Detailangaben
Hauptverfasser: LAN XIAOHUAN, ZHAO YOUYING, XU YONGBIN, ZHANG ZHIJIE, YANG LIYING, XIONG MEILING, JI XIANGXIN, CUI JIA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a composite collagen-based wound dressing containing rare earth ions and a preparation method of the composite collagen-based wound dressing. The composite collagen-based wound dressing containing the rare earth ions is prepared by taking collagen, polysaccharide and a rare earth compound as raw materials. Mixing a rare earth compound with the extracted collagen solution to obtain a collagen-rare earth ion mixed solution, and enabling the solution to have a bacteriostatic effect; dialdehyde polysaccharide prepared through oxidation modification is mixed with a collagen-rare earth ion mixed solution, the dialdehyde polysaccharide serves as a cross-linking agent, after the solution is completely mixed to be uniform, the mixed solution is subjected to freeze drying, and the composite collagen-based wound dressing containing the rare earth ions is obtained. Due to the addition of the dialdehyde polysaccharide, the mechanical strength of the dressing is increased, and the physicochemical pro