Specific binding agent of anti-Nectin-4 monoclonal antibody drug or derivative thereof and application of specific binding agent

The invention provides a binding agent capable of specifically binding an anti-Nectin-4 monoclonal antibody drug or a derivative thereof, the binding agent can block or not block the binding of the anti-Nectin-4 monoclonal antibody drug or the derivative thereof and an antigen Nectin-4, and the binding agent can be used for specifically detecting the anti-Nectin-4 monoclonal antibody drug or the derivative thereof in a sample. The drug or the derivative thereof is quantified and monitored, and is further used for immunogenicity analysis, pharmacokinetic analysis and the like. 本发明提供了一种特异性结合抗Nectin-4单克隆抗体药物或其衍生物的结合剂，所述结合剂能够阻断或者不阻断该抗Nectin-4单克隆抗体药物或其衍生物与抗原Nectin-4的结合，可用于特异性检测样品中抗Nectin-4单克隆抗体药物或其衍生物，以进行所述药物或其衍生物的量化和监测，进而用于其免疫原性分析、药代动力学分析等。