Application of 2-(2-phenethyl) chromone derivative in preparation of medicine for treating lung cancer
The invention belongs to the field of medicines, and relates to application of a 2-(2-phenethyl) chromone derivative in preparation of a medicine for treating lung cancer. CCK8 cell viability experiments and cell cycle detection experiments find that 6, 7-dihydroxy-2-(2-phenethyl) chromone can inhib...
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Zusammenfassung: | The invention belongs to the field of medicines, and relates to application of a 2-(2-phenethyl) chromone derivative in preparation of a medicine for treating lung cancer. CCK8 cell viability experiments and cell cycle detection experiments find that 6, 7-dihydroxy-2-(2-phenethyl) chromone can inhibit the cell viability of human lung cancer cells H23, H358 and A549 and retard the cell cycle in the G1 phase, it is verified that 6, 7-dihydroxy-2-(2-phenethyl) chromone has the lung cancer resisting effect, and it is indicated that 6, 7-dihydroxy-2-(2-phenethyl) chromone can be used for preparing a medicine for treating lung cancer. The 2, 7-dihydroxy-2-(2-phenethyl) chromone has an application prospect in preparation of the medicine for treating the lung cancer.
本发明属于医药领域,涉及一种2-(2-苯乙基)色酮衍生物在制备治疗肺癌药物中的应用。本发明通过CCK8细胞活力实验和细胞周期检测实验,发现6,7-二羟基-2-(2-苯乙基)色酮可以抑制人肺癌细胞H23、H358和A549的细胞活力、将细胞周期阻滞于G1期,验证了6,7-二羟基-2-(2-苯乙基)色酮具有抗肺癌的作用,表明了6,7-二羟基-2-(2-苯乙基)色酮在制备治疗肺癌的药物中具有应用前景。 |
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