Preparation method of R-type glassine

The invention discloses a preparation method of an R-type glassine, which comprises the following steps: mixing acetylacetone and xylose in an alkaline substance aqueous solution, heating to react, mixing the obtained first intermediate crude product with a biological enzyme, beta-nicotinamide adenine dinucleotide phosphate monosodium salt coenzyme and isopropanol in a buffer solution system, reacting at 30-40 DEG C, filtering, washing, and drying to obtain the R-type glassine. And obtaining the R-configuration glassine. According to the present invention, the R-configuration glassine with three-dimensional specific selectivity is obtained, the conversion rate is high, the product is easily separated and purified, the problems of low three-dimensional selectivity and difficult industrial production in the prior art are overcome, and the enterprise production cost is further reduced. 本发明公开了一种R型玻色因的制备方法，通过在碱性物质水溶液中将乙酰丙酮和木糖混合加热反应，将所得的第一中间产物粗品与生物酶、β-烟酰胺腺嘌呤二核苷酸磷酸单钠盐辅酶和异丙醇在缓冲溶液体系中混合，在30～40℃条件下反应，得到R-构型玻色因。本发明得到立体专一