Casein-source active peptide with immunocompetence as well as preparation method and application of casein-source active peptide

The invention discloses a casein-source active peptide with immunocompetence as well as a preparation method and application thereof, and relates to the technical field of biology. The amino acid sequence of the casein source immunoactive peptide is obtained by utilizing a separation and purification technology and a mass spectrum identification technology and by virtue of a protein database of casein. The immunocompetence peptide provided by the invention can have good immunocompetence and no biotoxicity, and can effectively promote RAW264.7 macrophages to generate immune response. 本发明公开了一种具有免疫活性的酪蛋白源活性肽及其制备方法和应用，涉及生物技术领域。本发明利用分离纯化技术和质谱鉴定技术，借助酪蛋白的蛋白质数据库，得到酪蛋白源免疫活性肽的氨基酸序列。本发明提供的免疫活性肽能够具有良好的免疫活性，无生物毒性，有效促进RAW264.7巨噬细胞产生免疫反应。