Method for producing alkyl furan carboxylic acid ester
Provided is a novel method for producing an alkyl furan carboxylic acid ester. A method for producing an alkylfuran carboxylic acid ester, which comprises performing a redox reaction between an alkylfuran aldehyde and a compound represented by A-OH (wherein A is an organic group having 1-10 carbon a...
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Sprache: | chi ; eng |
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Zusammenfassung: | Provided is a novel method for producing an alkyl furan carboxylic acid ester. A method for producing an alkylfuran carboxylic acid ester, which comprises performing a redox reaction between an alkylfuran aldehyde and a compound represented by A-OH (wherein A is an organic group having 1-10 carbon atoms) in the presence of a catalyst and a base, the catalyst being an N-heterocyclic carbene having a pKa of 33.0 or less, and the alkali being a metal oxide having a pKa of 33.0 or less. The pKa is calculated from free energy by determining the stable structure of the catalyst molecule in methanol by an SMD method using Gaussian 16.
提供新的烷基呋喃羧酸酯的制造方法。一种烷基呋喃羧酸酯的制造方法,其包括:在催化剂和碱的存在下,在烷基呋喃醛与A-OH所示的化合物(其中,A为碳原子数1~10的有机基团)之间进行氧化还原反应,催化剂是pKa为33.0以下的N-杂环状卡宾,所述pKa是使用Gaussian16并通过SMD法求出甲醇中的催化剂分子的稳定结构,并根据自由能而算出的。 |
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