Alzheimer's disease protein marker detection module, preparation method and application thereof

Alzheimer's disease protein marker detection module, preparation method and application thereof

The invention belongs to the technical field of biochemical sensing and in-vitro diagnosis, and particularly relates to an Alzheimer's disease protein marker detection module as well as a preparation method and application thereof. The method comprises the following steps: depositing a metal el...

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Hauptverfasser: GUO BIYU, LU YE
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Sprache:chi ; eng
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INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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creator GUO BIYU
LU YE
description The invention belongs to the technical field of biochemical sensing and in-vitro diagnosis, and particularly relates to an Alzheimer's disease protein marker detection module as well as a preparation method and application thereof. The method comprises the following steps: depositing a metal electrode on a silicon insulating substrate; graphene is transferred to the substrate plated with the metal electrode; sequentially dropwise adding a DNA aptamer with one modified end, polyethylene glycol and ethanolamine to the surface of the graphene channel for functionalization; according to the detection module, charged molecules are fixed to the surface of a graphene channel, the conductivity of the surface of the channel is changed, and therefore high-sensitivity and rapid detection of the Alzheimer's disease protein biomarker is achieved; according to the present invention, with the detection method, the requirement of the clinical rapid detection of one or more protein markers of the Alzheimer's disease by using
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title Alzheimer's disease protein marker detection module, preparation method and application thereof
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