Nucleic acid releasing agent, method for releasing nucleic acid and application

The invention discloses a nucleic acid releasing agent, a method for releasing nucleic acid and application. The nucleic acid releasing agent comprises a first component and a second component, wherein the first component comprises a metal chelating agent and a regulator for providing an alkaline environment; and the second component comprises trihydroxymethyl methylamino propanesulfonic acid and an ion providing agent. The method comprises the following steps: mixing the first component and the second component with a to-be-detected sample in sequence to complete nucleic acid release of the to-be-detected sample. The nucleic acid releasing agent can rapidly and effectively treat serum, plasma, swabs and whole blood samples and release nucleic acid under the room temperature condition, the PCR inhibition is reduced, the detection sensitivity is improved, the matched HBV detection can reach 10 IU/mL detection sensitivity, the operation method is simple, convenient and rapid, and the cost is low. 本发明公开了一种核酸释放剂、