Pyridone compound as well as preparation method, pharmaceutical composition and application thereof

The invention discloses a pyridone compound as well as a preparation method, a pharmaceutical composition and application thereof. The structure of the pyridone compound is shown as a formula (I), and the pyridone compound comprises an isomer, a pharmaceutically acceptable salt or a mixture of the isomer and the pharmaceutically acceptable salt. The pyridone compound has an efficient inhibition effect on cIAP1, cIAP2, XIAP and a variety of tumor cells, and can be used for preparing anti-tumor drugs which can exert drug effects at a molecular level and a cellular level. # imgabs0 # 本发明公开了一类吡啶酮类化合物及其制备方法、药物组合物和应用。该吡啶酮类化合物的结构如式(I)，该吡啶酮类化合物包含其异构体、药学上可接受的盐或它们的混合物。该吡啶酮类化合物对cIAP1,cIAP2,XIAP和多种肿瘤细胞均具有高效的抑制作用，可用于制备在分子水平和细胞水平均可以发挥药效的抗肿瘤药物。#imgabs0#