Micro-channel preparation method of o-nitrobenzaldehyde

The invention relates to a micro-channel preparation method of o-nitrobenzaldehyde, and relates to the field of medicine synthesis, the method comprises the following steps: taking o-nitrotoluene as a raw material and liquid bromine as a bromine source, under the initiation of a catalyst, continuously carrying out a substitution reaction through a micro-channel reactor to generate o-nitrobenzyl bromide; hydrolyzing o-nitrobenzyl bromide in a carbonate solution to form o-nitrobenzyl alcohol; and continuously oxidizing through the micro-channel reactor to obtain o-nitrobenzaldehyde. The o-nitrobenzaldehyde is prepared by using the micro-channel reactor, the raw materials are cheap and easy to obtain, the operation is simple, the process is simple, and the reaction time is greatly shortened. The preparation method is short in period, simple in process and suitable for industrial production. 本发明为一种邻硝基苯甲醛的微通道制备方法，涉及医药合成领域，该方法以邻硝基甲苯为原料，液溴为溴源，在催化剂的引发下，连续通过微通道反应器进行取代反应生成邻硝基苄溴；邻硝基苄溴在碳酸盐溶液中水解形成邻硝基苯甲醇；继续通过微通道反应器氧化得到邻硝基苯