Nicodil oral soluble film agent and preparation method thereof

The invention relates to a Nicodil oral soluble film agent. Each unit dose of the Nicodil oral soluble film agent comprises 1 to 4 mg of Nicodil, 30.0 to 60.0 wt% of a film forming agent, 20.0 to 45.0 wt% of a plasticizer, 5.0 to 15.0 wt% of a solubilizer and 1.0 to 5.0 wt% of a flavoring agent. The preparation method of the Nicodil oral soluble film agent comprises the following steps: S1, grinding Nicodil, dissolving the Nicodil, a plasticizer, a solubilizer and a corrigent in an ethanol water solution for dissolving, then adding a film-forming agent, and uniformly stirring to obtain a medicine solution; and S2, degassing, coating and drying the medicine solution obtained in the step S1 to obtain the Nicodil oral dissolving film agent. By selecting proper auxiliary materials and combining the scientific and reasonable proportion, the invention provides a preparation technology of preparation, freeze vacuum degassing and tape casting film coating of the Nicodil oral soluble film agent, so that the Nicodil or