Temperature-sensitive antipyretic gel and preparation method thereof

The invention discloses temperature-sensitive antipyretic gel and a preparation method thereof, and relates to the technical field of medical instruments. The preparation process comprises the following steps: (1) adding the cross-linking agent into purified water accounting for 70% of the formula a...

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Bibliographische Detailangaben
Hauptverfasser: ZHANG JIACHENG, DING JIAYAO, CAO JUN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses temperature-sensitive antipyretic gel and a preparation method thereof, and relates to the technical field of medical instruments. The preparation process comprises the following steps: (1) adding the cross-linking agent into purified water accounting for 70% of the formula amount, stirring and dissolving to prepare a solution A; (2) adding cooling factors into the solution A, and uniformly stirring to obtain a solution B; (3) adding poloxamer 188 and poloxamer 407 into the solution B, stirring, sealing, and putting into a refrigerator for cold dissolving to prepare a gel compound; and (4) after complete cold dissolution, adding the balance of purified water into the gel compound prepared in the step (3), uniformly stirring, sealing, and standing at room temperature to obtain the temperature-sensitive antipyretic gel. According to the antipyretic gel prepared by the invention, the gelling temperature is 30-33 DEG C, secondary cooling is realized through heat absorption gelling and phys