Anti-TCR delta variable 1 antibody

The present invention provides high affinity anti-TCR [delta] variable 1 (anti-V [delta] 1) antibodies and antibody fragments thereof. The invention also provides compositions and pharmaceutical compositions comprising such antibodies, as well as methods of making such antibodies. The invention also...

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Bibliographische Detailangaben
Hauptverfasser: TUNA MIHRIT, POLYAKOVA OLGA, MCKINLEY ANTHONY, UDEN MARK, MOUNT NEIL, FOCKLER DAVID, GOOD ROMAN, BUMBRA SANDEEP, FREEDMAN JONATHAN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention provides high affinity anti-TCR [delta] variable 1 (anti-V [delta] 1) antibodies and antibody fragments thereof. The invention also provides compositions and pharmaceutical compositions comprising such antibodies, as well as methods of making such antibodies. The invention also provides methods of treatment and medical uses involving said antibodies. 本发明提供了高亲和力抗TCRδ可变1(抗Vδ1)抗体和其抗体片段。本发明还提供了包含这类抗体的组合物和药物组合物,以及制备这类抗体的方法。本发明还提供了涉及所述抗体的治疗方法和医学用途。