Bacteroides strain and application thereof in degradation preparation of hyaluronic acid oligosaccharide

The invention relates to the field of degradation preparation of active oligosaccharides, in particular to a bacteroides strain and application thereof in degradation preparation of hyaluronic acid oligosaccharides. The strain of the bacteroides Zhangwenhongii is specifically a bacteroides Zhangwenh...

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Hauptverfasser: LI JIAYI, YANG MENGLIN, YU GUANGLI, LYU YOUJING, SHANG QINGSEN, FANG ZIYI, MA MINGFENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the field of degradation preparation of active oligosaccharides, in particular to a bacteroides strain and application thereof in degradation preparation of hyaluronic acid oligosaccharides. The strain of the bacteroides Zhangwenhongii is specifically a bacteroides Zhangwenhongii strain D2-16, the strain is separated from faeces of healthy human bodies and is preserved in the China Center for Type Culture Collection (CCTCC), and the preservation number is CCTCC NO: M 20232720. The invention further discloses a method for preparing the strain of the bacteroides Zhangwenhongii by using the strain of the bacteroides Zhangwenhongii. The strain can degrade hyaluronic acid into unsaturated hyaluronic acid oligosaccharide with the polymerization degree mainly being 4. 本发明涉及活性寡糖的降解制备领域,具体涉及一种张文宏拟杆菌菌株及其在降解制备透明质酸寡糖中的应用。张文宏拟杆菌菌株具体为张文宏拟杆菌菌株D2-16(Bacteroides zhangwenhongii D2-16),该菌株分离自健康人体粪便,保藏于中国典型培养物保藏中心,保藏编号为CCTCC NO:M 20232720。该菌株能够将透明质酸降解为聚合度主要为4的不饱和透明质酸寡糖。