Preparation method of tembotrione

The invention discloses a preparation method of tembotrione. The preparation method comprises the following steps: carrying out a rearrangement reaction on 2-chloro-3-cyclohexyloxymethyl-4-methyl xanthoyl benzoic acid 3-oxo-1-cyclohexene ester in the presence of alkali and a catalyst to obtain the t...

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Hauptverfasser: FU RENJI, XING WENLONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a preparation method of tembotrione. The preparation method comprises the following steps: carrying out a rearrangement reaction on 2-chloro-3-cyclohexyloxymethyl-4-methyl xanthoyl benzoic acid 3-oxo-1-cyclohexene ester in the presence of alkali and a catalyst to obtain the tembotrione, wherein the rearrangement reaction is carried out on the 2-chloro-3-cyclohexyloxymethyl-4-methyl xanthoyl benzoic acid 3-oxo-1-cyclohexene ester; the synthetic route is as follows: # imgabs0 #. The method is simple, convenient, safe, green, environment-friendly, high in conversion rate and low in product synthesis cost, and can well meet the requirements of industrial mass production. 本发明公开一种环磺酮的制备方法,其包括如下步骤:2-氯-3-环己基氧基甲基-4-甲基黄酰基苯甲酸3-氧代-1-环己烯酯在碱和催化剂存在下重排反应得到环磺酮;其合成路线如下:#imgabs0#。该方法简便、安全、绿色环保、高转化率、产品合成成本低,能够很好地满足工业化大生产的需求。