Methods of treating cancer and/or cancer metastasis

The present invention relates to a method of treating cancer and/or cancer metastasis in a subject comprising administering to the subject mesoporous silica nanoparticles loaded with irinotecan. The present invention also provides a combination comprising mesoporous silica nanoparticles (MSN) loaded...

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Bibliographische Detailangaben
Hauptverfasser:	OH JUNG-HOON, CHEN YIPING, ZHANG RONGLIN, WU SIHAN, MOU ZHONGYUAN, LI YUZE
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MANUFACTURE OR TREATMENT OF NANOSTRUCTURES MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES MEDICAL OR VETERINARY SCIENCE NANOTECHNOLOGY PERFORMING OPERATIONS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES TRANSPORTING
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Beschreibung
Zusammenfassung:	The present invention relates to a method of treating cancer and/or cancer metastasis in a subject comprising administering to the subject mesoporous silica nanoparticles loaded with irinotecan. The present invention also provides a combination comprising mesoporous silica nanoparticles (MSN) loaded with a medicament, the mesoporous silica nanoparticles defining at least one pore and having at least one functional group on a sidewall of the at least one pore. 本发明为涉及一种治疗个体的癌症及/或癌症转移的方法，其包含向所述个体投与装载有伊立替康(irinotecan)的中孔二氧化硅奈米粒子。本发明亦提供一种结合物，其包含装载有药剂的中孔二氧化硅奈米粒子(MSN)，所述中孔二氧化硅奈米粒子界定至少一个孔且在所述至少一个孔的侧壁上具有至少一种官能基。