Anti-CTLA-4 binding proteins and methods of use thereof

Provided herein are antigen binding proteins (ABPs) having binding specificity for CTLA-4 and compositions, including pharmaceutical compositions, diagnostic compositions, and kits, comprising such ABPs. Also provided are methods of making CTLA-4ABP, and methods of using CTLA-4ABP for, for example,...

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Hauptverfasser: JOHNSON DOUGLAS SCOTT, ADLER ADAM S, LIN YONGWEN, MIZRAHI ROBERT A, ISENHUGH MARK, STONE, EDWARD, L
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creator JOHNSON DOUGLAS SCOTT
ADLER ADAM S
LIN YONGWEN
MIZRAHI ROBERT A
ISENHUGH MARK
STONE, EDWARD, L
description Provided herein are antigen binding proteins (ABPs) having binding specificity for CTLA-4 and compositions, including pharmaceutical compositions, diagnostic compositions, and kits, comprising such ABPs. Also provided are methods of making CTLA-4ABP, and methods of using CTLA-4ABP for, for example, therapeutic purposes, such as treatment of cancer, diagnostic purposes, and research purposes. 本文提供了对CTLA-4具有结合特异性的抗原结合蛋白(ABP)和包含此类ABP的组合物,包括药物组合物、诊断组合物和试剂盒。还提供了制备CTLA-4ABP的方法,以及将CTLA-4ABP用于例如治疗目的诸如治疗癌症、诊断目的和研究目的的方法。
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language chi ; eng
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Anti-CTLA-4 binding proteins and methods of use thereof
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