Application of substance for detecting expression level of basophilic granulocyte CD282

The invention relates to the technical field of flow cytometry detection, in particular to application of a substance for detecting the expression level of basophilic granulocyte CD282, and the substance for detecting the expression level of basophilic granulocyte CD282 is used for preparing a sepsi...

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Bibliographische Detailangaben
Hauptverfasser: DONG ZIYI, ZHAN MENGMENG, JIN BYOUNG-OK, WANG JUNLING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of flow cytometry detection, in particular to application of a substance for detecting the expression level of basophilic granulocyte CD282, and the substance for detecting the expression level of basophilic granulocyte CD282 is used for preparing a sepsis diagnostic kit. The core component of the kit is a fluorescent dye labeled anti-human CD193 antibody and an anti-human CD282 antibody. Compared with healthy people, the expression level of basophilic granulocytes CD282 in peripheral venous blood is increased, and it is shown that a subject suffers from sepsis or has the risk of suffering from sepsis. The kit provided by the invention has simple and easily available components, and the detection method is simple, rapid and convenient, and has extremely profound significance for improving and guaranteeing the life quality and body health of sepsis patients. 本发明涉及流式细胞术检测技术领域,具体涉及检测嗜碱性粒细胞CD282表达水平的物质的应用,所述检测嗜碱性粒细胞CD282表达水平的物质用于制备脓毒症诊断试剂盒。所述试剂盒的核心成分为荧光染料标记的抗人CD193抗体和抗