Method for simultaneously detecting double active components in dapagliflozin and metformin sustained release tablet

The invention discloses a method for simultaneously detecting double active components in a dapagliflozin and metformin sustained release tablet. The method comprises the following steps: simultaneously detecting the contents of dapagliflozin and metformin in the dapagliflozin and metformin sustaine...

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Hauptverfasser: SI WENQI, JIANG HONGSHENG, XU PENG, XIA QING, QI WEI, HUO ZHENG, DU HONGSHAN, WANG ZIJUAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a method for simultaneously detecting double active components in a dapagliflozin and metformin sustained release tablet. The method comprises the following steps: simultaneously detecting the contents of dapagliflozin and metformin in the dapagliflozin and metformin sustained release tablet by adopting a high performance liquid chromatography method, a chromatographic column is a C18 column; a mobile phase A is 0.01%-0.1% of trifluoroacetic acid-water; and the mobile phase B is 0.01%-0.1% of trifluoroacetic acid-acetonitrile. 本发明公开了达格列净二甲双胍缓释片中双活性成分同时检测的方法,包括如下步骤:采用高效液相色谱方法对达格列净二甲双胍缓释片中达格列净和二甲双胍的含量同时进行检测;色谱柱为C18柱;流动相A:0.01%~0.1%三氟乙酸-水;流动相B:0.01%~0.1%三氟乙酸-乙腈。