Preparation method of photo-thermal synergistic polysaccharide-based fiber gel dressing and dressing thereof

The preparation method comprises the following steps: uniformly mixing a polyvinyl alcohol solution with an acylation modified chitosan solution, and then mixing the mixture with an epidermal growth factor (EGF) to obtain a spinning solution A for later use; uniformly mixing a polyvinyl alcohol solu...

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Hauptverfasser: LIU YI, DAI JINGLUN, SHU JIE, XU WEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The preparation method comprises the following steps: uniformly mixing a polyvinyl alcohol solution with an acylation modified chitosan solution, and then mixing the mixture with an epidermal growth factor (EGF) to obtain a spinning solution A for later use; uniformly mixing a polyvinyl alcohol solution with a sodium alginate solution, and then mixing with chloroauric acid to obtain a spinning solution B for later use; taking the spinning solution A as a shell layer solution and the spinning solution B as a core layer solution, carrying out coaxial electrostatic spinning to obtain a fiber membrane, and carrying out gas-phase crosslinking to obtain the photo-thermal synergistic interaction polysaccharide-based fiber gel dressing cross-linked CS/EGF (at) SA-Au. The photo-thermal synergistic interaction polysaccharide-based fiber gel dressing is prepared by using a coaxial electrostatic spinning technology, can promote cell proliferation, and has a promoting effect on healing and regeneration of epidermis wounds