Medical application of limaprost

The invention discloses a new application of limaprost in the aspect of repairing various acute and chronic lung injuries. The lung injuries comprise acute lung injuries (ALI) caused by bacterial and virus infection, radiation-induced lung injuries, idiopathic and secondary pulmonary fibrosis, chron...

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Bibliographische Detailangaben
Hauptverfasser: LI ERYAO, FU MINGYUE, JI XIAORAN, GAN LELING, LI BOYAN, YUE ZHIYANG, ZHANG XUELIAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a new application of limaprost in the aspect of repairing various acute and chronic lung injuries. The lung injuries comprise acute lung injuries (ALI) caused by bacterial and virus infection, radiation-induced lung injuries, idiopathic and secondary pulmonary fibrosis, chronic obstructive pulmonary diseases, interstitial pulmonary diseases, pneumoconiosis and the like. The limaprost has affinity activity on a plurality of alveolar regeneration related targets at the same time, and pharmacological tests prove that the limaprost has a definite repairing effect on acute and chronic lung injuries. 本发明公开了利马前列素在各种急慢性肺损伤的修复方面的新用途,这些肺损伤包括:细菌、病毒感染引发的急性肺损伤(ALI),放射性肺损伤、特发性和继发性肺纤维化、慢性阻塞性肺病、间质性肺病、尘肺等。利马前列素同时对多个肺泡再生相关靶点具有亲和活性,药理试验证实其明确的急慢性肺损伤的修复作用。