Human transferrin receptor binding peptides

[Problem] To provide a novel peptide that binds to human transferrin receptor (hTfR). [Solution] A peptide having an amino acid sequence represented by Ala-Val-MePhe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-K (MePEG4c)-Arg-Phe-MeTyr-Cys (SEQ ID NO: 1), or comprising an amino acid sequence having one or more spec...

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Hauptverfasser: TAKAHASHI KENICHI, YODA EIJI, HASHIMOTO HIDEHIKO, TAKUWA MASANORI, ONOUCHI, TAKASHI, YAMAKOSHI SHUHEI, OUCHI MASAKI, FUJIYAMA SAKI
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creator TAKAHASHI KENICHI
YODA EIJI
HASHIMOTO HIDEHIKO
TAKUWA MASANORI
ONOUCHI, TAKASHI
YAMAKOSHI SHUHEI
OUCHI MASAKI
FUJIYAMA SAKI
description [Problem] To provide a novel peptide that binds to human transferrin receptor (hTfR). [Solution] A peptide having an amino acid sequence represented by Ala-Val-MePhe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-K (MePEG4c)-Arg-Phe-MeTyr-Cys (SEQ ID NO: 1), or comprising an amino acid sequence having one or more specified substitutions in the amino acid sequence represented by SEQ ID NO: 1. [解决课题]提供与人转铁蛋白受体(hTfR)结合的新颖的肽。[解决方案]一种肽,其具有以下的氨基酸序列:Ala-Val-MePhe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-K(MePEG4c)-Arg-Phe-MeTyr-Cys(序列号1)所记载的氨基酸序列,或包含在序列号1所记载的氨基酸序列中具有1以上的指定的取代的氨基酸序列。
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Human transferrin receptor binding peptides
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