Human transferrin receptor binding peptides

[Problem] To provide a novel peptide that binds to human transferrin receptor (hTfR). [Solution] A peptide having an amino acid sequence represented by Ala-Val-MePhe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-K (MePEG4c)-Arg-Phe-MeTyr-Cys (SEQ ID NO: 1), or comprising an amino acid sequence having one or more spec...

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Hauptverfasser:	TAKAHASHI KENICHI, YODA EIJI, HASHIMOTO HIDEHIKO, TAKUWA MASANORI, ONOUCHI, TAKASHI, YAMAKOSHI SHUHEI, OUCHI MASAKI, FUJIYAMA SAKI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	[Problem] To provide a novel peptide that binds to human transferrin receptor (hTfR). [Solution] A peptide having an amino acid sequence represented by Ala-Val-MePhe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-K (MePEG4c)-Arg-Phe-MeTyr-Cys (SEQ ID NO: 1), or comprising an amino acid sequence having one or more specified substitutions in the amino acid sequence represented by SEQ ID NO: 1. [解决课题]提供与人转铁蛋白受体(hTfR)结合的新颖的肽。[解决方案]一种肽，其具有以下的氨基酸序列：Ala－Val－MePhe－Val－Trp－Asn－Tyr－Tyr－Ile－Ile－K(MePEG4c)－Arg－Phe－MeTyr－Cys(序列号1)所记载的氨基酸序列，或包含在序列号1所记载的氨基酸序列中具有1以上的指定的取代的氨基酸序列。